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National Heart Centre Singapore unveils AI for rapid coronary artery disease prediction

It is set to try out the technology with the National University Hospital and Tan Tock Seng Hospital.
By Adam Ang
National Heart Centre Singapore's CVS.ai researchers
Photo courtesy of the National Heart Centre Singapore

The National Heart Centre Singapore is set to pilot a new AI-powered solution for rapid coronary artery disease prediction.

SENSE (Singapore Heart Lesion Analyser) is a machine learning-driven system that can automatically interpret heart image scans and evaluate risk for CAD. It deploys AI algorithms and patented post-processing technologies to analyse four CAD parameters from CT scans: coronary calcium scores, epicardial adipose tissue, coronary stenosis, and plaque. These initial CAD determinants were highlighted by the NHCS APOLLO cardiac database.

According to NHCS, SENSE can generate reports for clinicians "within 10 minutes," which improves from the typical two to four hours processing time.

WHY IT MATTERS

CAD accounts for nearly a third of cardiovascular-related deaths in Singapore. The NHCS seeks to further prevent these deaths by leveraging AI to early track and monitor such heart conditions as CAD.

The hospital, through the CardioVascular Systems Imaging and Artificial Intelligence Research Laboratory (CVS.AI), leads the SENSE project with A*STAR Institute for Infocomm Research. Established in 2021, the laboratory has recently moved to a new facility and expanded its fleet of GPUs, which now enables the real-time processing of large datasets. 

SENSE also builds on CVS.AI's flagship project, the APOLLO database, which holds around three million heart images and information from approximately 5,000 patients across major heart centres in the country.

"SENSE provides high precision in predicting CAD, allowing clinicians to implement timely and appropriate intervention and treatment strategies," underscored Lohendran Baskaran, NHCS assistant professor and director and core clinical lead of CVS.AI. 

In addition to the NHCS, the CAD prediction tool will also be piloted at two other major cardiac hospitals, the National University Hospital and Tan Tock Seng Hospital (TTSH), in the third quarter of the year.

THE LARGER TREND

Health BETA, a Singaporean startup, is also working on an AI-powered solution to assess a person's risk for CAD. The tool utilises Asian genomics data to produce an enhanced polygenic risk score for CAD. According to founders Tan Kae Yuan and Heng Chew Kiat, the solution is slated for release sometime this year.